Review



fos creer t2 mice  (Jackson Laboratory)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 86
      Buy from Supplier

    Structured Review

    Jackson Laboratory fos creer t2 mice
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Fos Creer T2 Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc13178568-207-0-3?v=Jackson+Laboratory
    Average 86 stars, based on 1 article reviews
    fos creer t2 mice - by Bioz Stars, 2026-07
    86/100 stars

    Images

    1) Product Images from "Hcn1-dependent engram neurons in the PVN encode gastric inflammatory sensitization"

    Article Title: Hcn1-dependent engram neurons in the PVN encode gastric inflammatory sensitization

    Journal: Science Advances

    doi: 10.1126/sciadv.aeb6961

    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Figure Legend Snippet: ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].

    Techniques Used: Staining, Expressing, Retrograde Tracing, Saline, Immunofluorescence, Control

    ( A ) Schematic of the water-immersion RS-induced gastritis model. ( B ) Gross morphological appearance of gastric tissues in mice. ( C and D ) Gastric mucosal injury scores and representative H&E-stained sections ( n = 6 mice; two-tailed unpaired t test). ( E ) Stress significantly elevated levels of inflammatory cytokines IL-1β and TNF-α in gastric tissues compared to controls ( n = 6; two-tailed t test). ( F ) Representative Fos immunofluorescence images in PVN from control and stressed mice. ( G ) Increased Fos expression in the PVN of stressed mice versus controls ( n = 6; two-tailed t test). ( H ) Elevated serum corticosterone levels in stressed mice ( n = 7; two-tailed t test). ( I and J ) Enhanced gastric nerve firing frequency following stress exposure ( n = 5; two-tailed t test). ( K ) Experimental timeline for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice subjected to RS. ( L ) Representative images showing PRV-EGFP + neurons colocalized with Fos + cells across brain regions. ( M ) Quantification of Fos/PRV colocalization rates in different brain areas.
    Figure Legend Snippet: ( A ) Schematic of the water-immersion RS-induced gastritis model. ( B ) Gross morphological appearance of gastric tissues in mice. ( C and D ) Gastric mucosal injury scores and representative H&E-stained sections ( n = 6 mice; two-tailed unpaired t test). ( E ) Stress significantly elevated levels of inflammatory cytokines IL-1β and TNF-α in gastric tissues compared to controls ( n = 6; two-tailed t test). ( F ) Representative Fos immunofluorescence images in PVN from control and stressed mice. ( G ) Increased Fos expression in the PVN of stressed mice versus controls ( n = 6; two-tailed t test). ( H ) Elevated serum corticosterone levels in stressed mice ( n = 7; two-tailed t test). ( I and J ) Enhanced gastric nerve firing frequency following stress exposure ( n = 5; two-tailed t test). ( K ) Experimental timeline for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice subjected to RS. ( L ) Representative images showing PRV-EGFP + neurons colocalized with Fos + cells across brain regions. ( M ) Quantification of Fos/PRV colocalization rates in different brain areas.

    Techniques Used: Staining, Two Tailed Test, Immunofluorescence, Control, Expressing, Retrograde Tracing



    Similar Products

    fos creer t2 mice  (Jackson Laboratory)
    86
    Jackson Laboratory fos creer t2 mice
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Fos Creer T2 Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc13178568-207-0-3?v=Jackson+Laboratory
    Average 86 stars, based on 1 article reviews
    fos creer t2 mice - by Bioz Stars, 2026-07
    86/100 stars
    		  Buy from Supplier
    fos-creer t2 mice 021882  (Jackson Laboratory)
    90
    Jackson Laboratory fos-creer t2 mice 021882
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Fos Creer T2 Mice 021882, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc10702843-192-11-19?v=Jackson+Laboratory
    Average 90 stars, based on 1 article reviews
    fos-creer t2 mice 021882 - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    fos-creer t2 mice  (Jackson Laboratory)
    90
    Jackson Laboratory fos-creer t2 mice
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Fos Creer T2 Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc08532193-111-21-32?v=Jackson+Laboratory
    Average 90 stars, based on 1 article reviews
    fos-creer t2 mice - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    transgenic mice fos-creer t2  (Jackson Laboratory)
    90
    Jackson Laboratory transgenic mice fos-creer t2
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Transgenic Mice Fos Creer T2, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc08334743-232-0-26?v=Jackson+Laboratory
    Average 90 stars, based on 1 article reviews
    transgenic mice fos-creer t2 - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    heterozygous fos-creer t2 mice  (Jackson Laboratory)
    90
    Jackson Laboratory heterozygous fos-creer t2 mice
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Heterozygous Fos Creer T2 Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc07069961-361-3-15?v=Jackson+Laboratory
    Average 90 stars, based on 1 article reviews
    heterozygous fos-creer t2 mice - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    fos-creer t2 (+/-) mice  (Jackson Laboratory)
    90
    Jackson Laboratory fos-creer t2 (+/-) mice
    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing <t>in</t> <t>Fos-CreER</t> <t>T2</t> × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].
    Fos Creer T2 (+/ ) Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fos+creer+t2+mice/pmc07069961-364-17-8?v=Jackson+Laboratory
    Average 90 stars, based on 1 article reviews
    fos-creer t2 (+/-) mice - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].

    Journal: Science Advances

    Article Title: Hcn1-dependent engram neurons in the PVN encode gastric inflammatory sensitization

    doi: 10.1126/sciadv.aeb6961

    Figure Lengend Snippet: ( A ) Schematic of the HCl/EtOH-induced gastritis model. h, hours. ( B ) Gross morphology of gastric tissues. ( C and D ) Histopathological analysis (C: H&E staining; D: mucosal injury score). ( E ) Elevated IL-1β and TNF-α levels in gastric tissues of gastritis mice. ( F ) TdTomato (TdT) expression in activated neurons post–4-OHT treatment. ( G ) Experimental workflow for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice. ( H ) Whole-brain mapping of PRV-EGFP + neurons in the saline group and the gastritis group in Fos-CreER T2 × Rosa-TdT mice. ( I ) Quantification of c-Fos/PRV-EGFP colocalization across brain regions in the saline group and the gastritis group. ( J ) Representative c-Fos immunofluorescence images of the saline group and the gastritis group. ( K ) c-Fos + neuron counts in gastritis versus control [ n = 6 mice; F (5,55) = 123.4, two-way ANOVA].

    Article Snippet: Fos-CreER T2 mice (the Jackson Laboratory, strain no. 030323) were crossed with Rosa-TdTomato reporter mice (the Jackson Laboratory, strain no. 007914) to generate Fos-CreER T2 × Rosa-TdT mice for neuronal labeling.

    Techniques: Staining, Expressing, Retrograde Tracing, Saline, Immunofluorescence, Control

    ( A ) Schematic of the water-immersion RS-induced gastritis model. ( B ) Gross morphological appearance of gastric tissues in mice. ( C and D ) Gastric mucosal injury scores and representative H&E-stained sections ( n = 6 mice; two-tailed unpaired t test). ( E ) Stress significantly elevated levels of inflammatory cytokines IL-1β and TNF-α in gastric tissues compared to controls ( n = 6; two-tailed t test). ( F ) Representative Fos immunofluorescence images in PVN from control and stressed mice. ( G ) Increased Fos expression in the PVN of stressed mice versus controls ( n = 6; two-tailed t test). ( H ) Elevated serum corticosterone levels in stressed mice ( n = 7; two-tailed t test). ( I and J ) Enhanced gastric nerve firing frequency following stress exposure ( n = 5; two-tailed t test). ( K ) Experimental timeline for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice subjected to RS. ( L ) Representative images showing PRV-EGFP + neurons colocalized with Fos + cells across brain regions. ( M ) Quantification of Fos/PRV colocalization rates in different brain areas.

    Journal: Science Advances

    Article Title: Hcn1-dependent engram neurons in the PVN encode gastric inflammatory sensitization

    doi: 10.1126/sciadv.aeb6961

    Figure Lengend Snippet: ( A ) Schematic of the water-immersion RS-induced gastritis model. ( B ) Gross morphological appearance of gastric tissues in mice. ( C and D ) Gastric mucosal injury scores and representative H&E-stained sections ( n = 6 mice; two-tailed unpaired t test). ( E ) Stress significantly elevated levels of inflammatory cytokines IL-1β and TNF-α in gastric tissues compared to controls ( n = 6; two-tailed t test). ( F ) Representative Fos immunofluorescence images in PVN from control and stressed mice. ( G ) Increased Fos expression in the PVN of stressed mice versus controls ( n = 6; two-tailed t test). ( H ) Elevated serum corticosterone levels in stressed mice ( n = 7; two-tailed t test). ( I and J ) Enhanced gastric nerve firing frequency following stress exposure ( n = 5; two-tailed t test). ( K ) Experimental timeline for PRV retrograde tracing in Fos-CreER T2 × Rosa-TdT mice subjected to RS. ( L ) Representative images showing PRV-EGFP + neurons colocalized with Fos + cells across brain regions. ( M ) Quantification of Fos/PRV colocalization rates in different brain areas.

    Article Snippet: Fos-CreER T2 mice (the Jackson Laboratory, strain no. 030323) were crossed with Rosa-TdTomato reporter mice (the Jackson Laboratory, strain no. 007914) to generate Fos-CreER T2 × Rosa-TdT mice for neuronal labeling.

    Techniques: Staining, Two Tailed Test, Immunofluorescence, Control, Expressing, Retrograde Tracing